Yihong Ye Selected Research

Neurodegenerative Diseases (Neurodegenerative Disease)

11/2023	Molecular Graph-Based Deep Learning Algorithm Facilitates an Imaging-Based Strategy for Rapid Discovery of Small Molecules Modulating Biomolecular Condensates.
1/2023	Abnormal triaging of misfolded proteins by adult neuronal ceroid lipofuscinosis-associated DNAJC5/CSPα mutants causes lipofuscin accumulation.
1/2018	DNAJC5 facilitates USP19-dependent unconventional secretion of misfolded cytosolic proteins.

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Yihong Ye Research Topics

Disease

8	Neoplasms (Cancer) 11/2023 - 02/2009
3	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2023 - 01/2018
3	Tauopathies 09/2023 - 01/2021
3	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 05/2006
3	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 08/2011 - 02/2009
2	COVID-19 01/2024 - 01/2022
2	Parkinson Disease (Parkinson's Disease) 11/2023 - 01/2020
2	Inflammation (Inflammations) 09/2023 - 08/2023
2	Gliosis 09/2023 - 08/2023
2	Starvation 01/2021 - 01/2018
2	Multiple Myeloma 11/2010 - 02/2009
1	Rheumatoid Arthritis 01/2023
1	Neuronal Ceroid-Lipofuscinoses (Neuronal Ceroid Lipofuscinosis) 01/2023
1	Infections 01/2022
1	Disease Progression 01/2022
1	Breakthrough Infections 01/2022
1	Cicatrix (Scar) 01/2020
1	Anemia 01/2020
1	Carcinogenesis 11/2015
1	Dystonia musculorum deformans type 1 07/2011
1	Machado-Joseph Disease (Spinocerebellar Ataxia Type 3) 07/2011
1	Spinocerebellar Ataxias (Spinocerebellar Ataxia) 09/2006

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 11/2023 - 09/2006
3	SynucleinsIBA 11/2023 - 01/2020
3	Carrier Proteins (Binding Protein)IBA 09/2023 - 01/2023
3	IntegrinsIBA 09/2023 - 01/2021
3	Bortezomib (Velcade)FDA Link 08/2011 - 02/2009
2	Deubiquitinating EnzymesIBA 11/2023 - 09/2006
2	UbiquitinIBA 01/2021 - 02/2009
2	Valosin Containing ProteinIBA 01/2019 - 11/2016
2	1- (4- chlorophenyl)- 3- (3- (4- chlorophenyl)- 5,5- dimethyl- 1- (3- (5- nitrofuran- 2- yl)allyldienehydrazinocarbonylmethyl)- 2- oxoimidazolidin- 4- yl)- 1- hydroxyureaIBA 11/2016 - 11/2010
2	ATPases Associated with Diverse Cellular ActivitiesIBA 07/2011 - 11/2010
2	Ataxin-3IBA 07/2011 - 09/2006
2	Proteasome InhibitorsIBA 11/2010 - 02/2009
2	PresenilinsIBA 08/2007 - 05/2006
1	Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA 01/2024
1	ChaperoninsIBA 11/2023
1	DNA-Binding Proteins (DNA Binding Protein)IBA 11/2023
1	Green Fluorescent ProteinsIBA 01/2023
1	palmitoyl-protein thioesteraseIBA 01/2023
1	Auranofin (Ridaura)FDA Link 01/2023
1	Cysteine (L-Cysteine)FDA Link 01/2023
1	Glutamine (L-Glutamine)FDA Link 01/2023
1	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2023
1	LipofuscinIBA 01/2023
1	Phosphotransferases (Kinase)IBA 01/2023
1	StreptavidinIBA 01/2023
1	Sirolimus (Rapamycin)FDA Link 01/2023
1	Heavy Chain Fusion Regulatory Protein 1IBA 01/2023
1	Small Interfering RNA (siRNA)IBA 01/2023
1	bafilomycin A1IBA 01/2023
1	ClusterinIBA 01/2023
1	Lysosomal-Associated Membrane Protein 1IBA 01/2023
1	Endosomal Sorting Complexes Required for TransportIBA 01/2023
1	DNA TopoisomerasesIBA 01/2022
1	VaccinesIBA 01/2022
1	Heparitin Sulfate (Heparan Sulfate)IBA 01/2022
1	Mitoxantrone (Novantrone)FDA LinkGeneric 01/2022
1	Protein AggregatesIBA 01/2021
1	Ligases (Synthetase)IBA 01/2021
1	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2021
1	Lysine (L-Lysine)FDA Link 01/2021
1	ClathrinIBA 01/2020
1	Adenosine Triphosphatases (ATPase)IBA 11/2015
1	AntioxidantsIBA 08/2011
1	polyglutamineIBA 07/2011
1	CalpainIBA 07/2011
1	Proteasome Endopeptidase Complex (Proteasome)IBA 02/2009
1	Flavin-Adenine Dinucleotide (FAD)IBA 05/2006

Therapy/Procedure

8	Therapeutics 01/2024 - 02/2009